Pyridine → HCID 13881473, compound

Participants

Reaction Steps

A mixture of 1.0 g (3.4 mmoles) of 1,3-bis(2',6'-dimethylphenyl)-2-imino-imidazolidine, prepared as described in Example 1, Method (a), 10 ml of 1,2-dichloroethane, 0.33 ml (0.32 g, 4.0 mmole) of dry pyridine and 0.46 ml (0.56 g, 4.0 mmoles) of benzoyl chloride is heated on a steam bath for 2 hours. The cooled mixture is washed thrice with 10 ml of water each, thrice with 10 ml of 10% aqueous sodium hydrogencarbonate solution each, and again thrice with 10 ml of water each, dried over anhydrous sodium sulfate, and the solvent is evaporated under reduced pressure. 1.0 g (74.1%) of crude 1,3-bis(2',6'-dimethylphenyl)-2-benzoylimino-imidazolidine are obtained. After recrystallization from aqueous methanol the product melts at 176°-178° C.

Provenance & Evidence