HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 1-(2-Chlorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine--hydrogen chloride (1/2)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-(Chloromethyl)-1,2,3-trimethoxybenzene | HCID 77448 | — |
| Reactant | 1-(2-Chlorophenyl)piperazine | HCID 415628 | — |
| Product | 1-(2-Chlorophenyl)-4-[(3,4,5-trimethoxyphenyl)methyl]piperazine--hydrogen chloride (1/2) | HCID 3062142 | 111.3% |
Reaction Steps
4.33 g of 3,4,5-trimethoxybenzyl chloride and 3.93 g of N-(2-chlorophenyl)-piperazine and 3.5 g of K2CO3 are reacted and processed according to example 2. 5.0 g of N-(3,4,5-trimethoxy-benzyl)-N'-(2-chlorophenyl)-piperazine dihydrochloride is obtained. Mp.: 225° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04370330 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-50fa0e623ba24a268a049f9f9fbc4fbd |
| Source note | uspto-grants-1983_01 |