HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Methoxyphenyl)piperazine → Piperazine, 1-(2-methoxyphenyl)-4-((3,4,5-trimethoxyphenyl)methyl)-, dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Methoxyphenyl)piperazine | HCID 1346 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-(Chloromethyl)-1,2,3-trimethoxybenzene | HCID 77448 | — |
| Product | Piperazine, 1-(2-methoxyphenyl)-4-((3,4,5-trimethoxyphenyl)methyl)-, dihydrochloride | HCID 3062143 | 112.3% |
Reaction Steps
3.85 g of N-(2-methoxyphenyl)-piperazine, 4.33 g of 3,4,5-trimethoxybenzyl chloride and 3.5 g of K2CO3 are reacted and processed according to example 2. 5.0 g of N-(3,4,5-trimethoxy-benzyl)-N'-(2-methoxyphenyl)-piperazine dihydrochloride is obtained. Mp.: 219° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04370330 |
| Source dataset | uspto-grants-1983_01 |
| ORD ID | ord-76aeb48a0e4148a58a53209b3c75f8f7 |
| Source note | uspto-grants-1983_01 |