Bromine → HCID 13097126, compound

HRID 1164528Notes

Reaction equation

HRID 1164528 reaction equation
[O:1]=[C:2]1[N:6]([CH2:7][C:8]([O:10][CH3:11])=[O:9])[C:5]2[CH:12]=[C:13]([Cl:16])[CH:14]=[CH:15][C:4]=2[S:3]1.[Br:17]Br>O1CCOCC1>[O:1]=[C:2]1[N:6]([CH2:7][C:8]([O:10][CH3:11])=[O:9])[C:5]2[CH:12]=[C:13]([Cl:16])[C:14]([Br:17])=[CH:15][C:4]=2[S:3]1

Participants

4

Reactant 2

HCID 24408BromineHCID 13040939Methyl 2-oxo-5-chloro-3-benzothiazolineacetate

Product 1

HCID 13097126HCID 13097126, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

To a solution of methyl 2-oxo-5-chloro-3-benzothiazolineacetate (10 g) in dioxane (100 ml) was added dropwise bromine (2 ml) with stirring at 25°-30° C. during 40 minutes. After the stirring was continued at ambient temperature for 4 hours, precipitates in the resultant mixture were separated by filtration, washed with dioxane and diethylether and dried to give crystalline methyl 2-oxo-5-chloro-6-bromo-3-benzothiazolineacetate (8.38 g).

Workup

  1. waitAfter the stirring was continued at ambient temperature for 4 hours
  2. customprecipitates in the resultant mixture
  3. customwere separated by filtration
  4. washwashed with dioxane and diethylether
  5. customdried

Sources & evidence

ORD record
ord-ab126b3e322b41e6855ce4beb131871b
Source dataset
uspto-grants-1983_01
Patent number
US04370340

Reaction notes

Loading…