Diphenylthiourea → Carbanilide

HRID 1164695Notes

Reaction equation

HRID 1164695 reaction equation
[C:1]1([NH:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=S)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C[O:18]C1C=CC([Te](C2C=CC(OC)=CC=2)=O)=CC=1>CO>[C:1]1([NH:7][C:8]([NH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:18])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 700999DiphenylthioureaHCID 3044917Bis(p-methoxyphenyl) telluroxide

Product 1

HCID 7595CarbanilideYield 68%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1,3-Diphenylthiourea (114 mg, 0,5 mmol) was reacted with bis-(p-methoxyphenyl)-telluroxide for 16 h (methanol as solvent), the methanol was evaporated off under vacuum, the residue triturated with benzene and filtered to afford 1,3-diphenylurea as a white solid (72 mg, 68%), m.p. 234° (lit., 238°-239°).

Workup

  1. customthe methanol was evaporated off under vacuum
  2. customthe residue triturated with benzene
  3. filtrationfiltered

Sources & evidence

ORD record
ord-e5126080760f44d99387f1488395a070
Source dataset
uspto-grants-1983_01
Patent number
US04370497

Reaction notes

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