Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethyl methoxymalonate → HCID 178442636, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethyl methoxymalonate | HCID 78718 | — |
| 반응물 | 4-Octylbenzamidine hydrochloride | HCID 13640876 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | HCID 178442636 | HCID 178442636 | 89.3% |
반응 단계
Metal sodium (23.4 g, 1.02 mol) was added to methanol (500 ml) to obtain sodium methoxide, followed by adding thereto 4-octylbenzamidine hydrochloride (84 g, 0.31 mol) and dimethyl methoxymalonate (55 g, 0.31 mol), refluxing the mixture for 8 hours, pouring the reaction mixture in acetic acid (500 ml), filtering off deposited crystals, washing them with water and drying to obtain 4,6-dihydroxy-5-methoxy-2-(4-octylphenyl)pyrimidine (91.5 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04906400 |
| 출처 데이터셋 | uspto-grants-1990_03 |
| ORD ID | ord-02e904e748a5401badc1c433090dffe5 |
| 출처 메모 | uspto-grants-1990_03 |