N-bromobutanimide → HCID 19863158, compound

Participants

Reaction Steps

A mixture of MOPPP (see Example 20d; 1.1 mmole) in dry CCl4 (10 ml) with N-bromosuccinimide (1.8 mmole) and a catalytic quantity of azo-isobutyronitril (5 mg) was heated for 24 hours. After cooling, the reaction mixture was purified directly by column chromatography (silica gel eluted with hexane/chloroform). MBOPP was recrystallised from hexane as fine needles (yield 45%; mp 104°-5° C.). The results of IR, 1H-NMR and mass spectroscopy and elemental analysis were consistent with the assigned structure.

Provenance & Evidence