HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 4-(Diethylphosphonomethyl)-2-pyridinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-Cyano-4-(diethylphosphonomethyl)pyridine | HCID 14541438 | — |
| Product | 4-(Diethylphosphonomethyl)-2-pyridinecarboxamide | HCID 14541439 | — |
Reaction Steps
A mixture of 1.10 g of 2-cyano-4-(diethylphosphonomethyl)pyridine and 4.5 ml of concentrated sulfuric acid is heated at 90° for 5 minutes. The reaction mixture is poured onto ice and neutralized with 10% sodium hydroxide. The resulting precipitate is collected to afford 4-(diethylphosphonomethyl)-2-pyridinecarboxamide melting at 140°-142°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04906621 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-83c1ca6c78a54466ad9efc1dd4ff8d6d |
| Source note | uspto-grants-1990_03 |