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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1164849Generated: October 27, 2026

m-Chloroperbenzoic acid → Pyridine-2-carbonitrile

https://huagongshe.com/reaction/1164849

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm-Chloroperbenzoic acidHCID 70297—
ReactantTrimethylsilyl cyanideHCID 82115—
Reactant3-(Diethoxyphosphorylmethyl)pyridineHCID 10462605—
ProductPyridine-2-carbonitrileHCID 7522—
Product5-(Diethylphosphonomethyl)-2-cyanopyridineHCID 54489936—

Reaction Steps

Treatment of 3-(diethylphosphonomethyl)pyridine (Biochemistry 19, 3400) with m-chloroperbenzoic acid followed by trimethylsilyl cyanide gives both 3-diethylphosphonomethyl)-2-cyanopyridine and 5-(diethylphosphonomethyl)-2-cyanopyridine, the starting materials for compounds under (a) and (b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04906621
Source datasetuspto-grants-1990_03
ORD IDord-06c1dc439c2c43099412986739386ee8
Source noteuspto-grants-1990_03