HCID 14850767, compound → HCID 131716302, compound

HRID 1164866Notes

Reaction equation

HRID 1164866 reaction equation
[CH2:1]([O:3][C:4]([N:6]1[CH2:10][CH:9]=[C:8]([CH2:11][P:12]([O:17][CH2:18][CH3:19])([O:14][CH2:15][CH3:16])=[O:13])[CH:7]1[C:20]([O:22][CH2:23][CH3:24])=[O:21])=[O:5])[CH3:2]>C(O)C.[Pd]>[CH2:1]([O:3][C:4]([N:6]1[CH2:10][CH2:9][C@@H:8]([CH2:11][P:12]([O:14][CH2:15][CH3:16])([O:17][CH2:18][CH3:19])=[O:13])[C@@H:7]1[C:20]([O:22][CH2:23][CH3:24])=[O:21])=[O:5])[CH3:2]

Participants

4

Reactant 1

HCID 14850767HCID 14850767, compound

Product 1

HCID 131716302HCID 131716302, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A solution of 2.75 g of ethyl 1-ethoxycarbonyl-3-(diethylphosphonomethyl)-2,5-dihydropyrrole-2-carboxylate in 35 ml ethyl alcohol and 1.5 g 10% Pd/C is hydrogenated at 3 atmospheres pressure to yield cis and trans ethyl 1-ethoxycarbonyl-3-(diethylphosphonomethyl)-pyrrolidine-2-carboxylate.

Sources & evidence

ORD record
ord-11650c632e424dc1831c81771571a61c
Source dataset
uspto-grants-1990_03
Patent number
US04906621

Reaction notes

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