HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → 4-(2-{[tert-Butyl(dimethyl)silyl]oxy}ethyl)-1-oxo-1lambda~5~-pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | 4-(Tert-butyldimethylsilyloxyethyl)-pyridine | HCID 22321619 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-(2-{[tert-Butyl(dimethyl)silyl]oxy}ethyl)-1-oxo-1lambda~5~-pyridine | HCID 19757789 | — |
Reaction Steps
To a stirred solution of 28.8 g of 4-(tert-butyl-dimethysilyloxyethyl)-pyridine in 300 ml of methylene chloride is added 24 g of m-chloroperbenzoic acid. After 4 hours the solution is washed with aqueous sodium carbonate solution and water. The solution is dried over sodium sulfate, filtered and concentrated in vacuo to yield 4-(tert-butyl-dimethylsilyloxyethyl)-pyridine-N-oxide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04906621 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-d5ec83961fca4c79aa35f578d6220eb9 |
| Source note | uspto-grants-1990_03 |