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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1164894Generated: November 2, 2026

cis 1-Ethoxycarbonyl-2-ethoxycarbonylpyrrolidine-3-ethanol → cis 1-Ethoxycarbonyl-2-ethoxycarbonylpyrrolidine-3-acetaldehyde

https://huagongshe.com/reaction/1164894

Reaction equation

Participants

RoleNameHCIDCharge
Reactantcis 1-Ethoxycarbonyl-2-ethoxycarbonylpyrrolidine-3-ethanolHCID 86743786—
ReactantHCID 178418287HCID 178418287—
SolventDichloromethaneHCID 6344—
Productcis 1-Ethoxycarbonyl-2-ethoxycarbonylpyrrolidine-3-acetaldehydeHCID 86743790—

Reaction Steps

A solution of 0.908 g of cis 1-ethoxycarbonyl-2-ethoxycarbonylpyrrolidine-3-ethanol and 1.14 g pyridinium chlorochromate in 20 ml of methylene chloride is stirred under nitrogen for 4 hours. Mixture is filtered and purified by flash chromatography using ethyl acetate/hexane (1:1) to yield cis 1-ethoxycarbonyl-2-ethoxycarbonylpyrrolidine-3-acetaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04906621
Source datasetuspto-grants-1990_03
ORD IDord-12a3cf00b53c4ae3aa701ef73a3d8136
Source noteuspto-grants-1990_03