Chlorosulfonic acid → HCID 22164315, compound

HRID 1164906Notes

Reaction equation

[Cl:1][C:2]1[S:3][CH:4]=[C:5]([Cl:7])[N:6]=1.[Cl:8][S:9](O)(=[O:11])=[O:10]>>[Cl:1][C:2]1([S:9]([Cl:8])(=[O:11])=[O:10])[NH:6][C:5]([Cl:7])=[CH:4][S:3]1

Participants

Reactant 2

HCID 24638Chlorosulfonic acid

HCID 123331552,4-Dichlorothiazole

Product 1

HCID 22164315HCID 22164315, compound

Procedure

can be prepared in a process in which, in a first step, 2,4-dichloro-thiazole is reacted with chlorosulphonic acid to give 2,4-dichloro-thiazole-sulphonyl chloride, in which, in a second step, the 2,4-dichloro-thiazole-sulphonyl chloride is reacted with primary amines or with a primary and a secondary amine to give 2-amino-4-chloro-thiazole-sulphonamides, and in which, in a third step, the sulphonamides mentioned are reacted with dichlorohalogenomethylsulphenyl chlorides to give the substances of the formula (I).

Sources & evidence

ORD record: ord-6a1de866981f4913874ea2e576c78b7c
Source dataset: uspto-grants-1990_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04906650

Reaction notes

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