Dimethylamine → HCID 22164313, compound

HRID 1164909Notes

Reaction equation

HRID 1164909 reaction equation
[Cl:1][C:2]1([S:8](Cl)(=[O:10])=[O:9])[NH:6][C:5]([Cl:7])=[CH:4][S:3]1.[CH3:12][NH:13][CH3:14]>>[CH3:12][N:13]([CH3:14])[S:8]([C:2]1([Cl:1])[NH:6][C:5]([Cl:7])=[CH:4][S:3]1)(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 674DimethylamineHCID 22164315HCID 22164315, compound

Product 1

HCID 22164313HCID 22164313, compound

Procedure

In analogy to Example 2, the N,N-dimethyl-2,4-dichlorothiazole-sulphonamide was prepared by reacting 2,4-dichlorothiazole-sulphonyl chloride from Example 1 with 45% strength dimethylamine solution. Following recrystallization from petroleum ether/acetone 6:1, 21.7 g of product were obtained (83% of the theoretical yield), m.p.: 89°-90° C.

Workup

  1. customrecrystallization from petroleum ether/acetone 6:1

Sources & evidence

ORD record
ord-467d1362674748ed88d4b2f77656b726
Source dataset
uspto-grants-1990_03
Patent number
US04906650

Reaction notes

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