Cycloheptaneacetic acid, 2-oxo-, ethyl ester → HCID 15228526, compound

HRID 1164923Notes

Reaction equation

HRID 1164923 reaction equation
O=[C:2]1[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4][CH:3]1[CH2:9][C:10]([O:12]CC)=[O:11].Cl.[CH3:16][S:17]([C:20]1[CH:35]=[CH:34][C:23]([CH2:24][N:25]([C:27]2[CH:32]=[CH:31][C:30]([F:33])=[CH:29][CH:28]=2)N)=[CH:22][CH:21]=1)(=[O:19])=[O:18]>>[F:33][C:30]1[CH:29]=[C:28]2[C:27](=[CH:32][CH:31]=1)[N:25]([CH2:24][C:23]1[CH:34]=[CH:35][C:20]([S:17]([CH3:16])(=[O:19])=[O:18])=[CH:21][CH:22]=1)[C:2]1[CH:3]([CH2:9][C:10]([OH:12])=[O:11])[CH2:4][CH2:5][CH2:6][CH2:7][C:8]2=1

Participants

3

Reactant 2

HCID 12251701Cycloheptaneacetic acid, 2-oxo-, ethyl esterHCID 19863700HCID 19863700, compound

Product 1

HCID 15228526HCID 15228526, compound

Procedure

Following the procedure of Example 1, but using ethyl 2-oxo-cycloheptaneacetate and 1-(p-methylsulfonylbenzyl)-1-(p-fluorophenyl)hydrazine hydrochloride as starting materials, the title compound is obtained.

Sources & evidence

ORD record
ord-847a82e6c62c43e9b2fb96b75d1bf66a
Source dataset
uspto-grants-1990_03
Patent number
US04906654

Reaction notes

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