Hydrochloric Acid → HCID 19863770, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2.0 g of 4-(4-methoxycarbonylmethylphenylamino)-2,3,6-trimethylphenol (Compound 86), 7.2 ml of 36% hydrochloric acid and 14.2 ml of acetic acid was heated at 50° C. for 14.5 hours. The reaction mixture was cooled to room temperature, and the crystals that precipitated were filtered, washed with acetonitrile and dried, giving 1.6 g of the title compound. The filtrate was concentrated under reduced pressure, and the solid thus obtained was treated similarly, additionally giving 0.4 g of the title compound.

Provenance & Evidence