Hexamethylenetetramine → HCID 14819303, compound

Participants

Reaction Steps

To a stirred mixture of 58.0 g (0.410 mole) of hexamethylenetetramine in 900 ml of chloroform was added 77.0 g (0.380 mole) of 2-bromo-1-thien-2-ylethanone. The mixture was stirred at room temperature for approximately 18 hours. A precipitate formed and was collected by filtration. The filter cake was washed with methylene chloride and was dried to yield 122.4 g of 1-(2-oxo-2-thien-2-ylethyl)-3,5,7-triaza-1-azoniatricyclo[3,3,1,13,7 ]decane bromide.

Provenance & Evidence