Cyclopentylamine → HCID 20098394, compound

HRID 1165232Notes

Reaction equation

HRID 1165232 reaction equation
Br[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[NH:12][C:13]([C:15]1[C:16]2[CH:17]=[CH:18][NH:19][C:20]=2[CH:21]=[CH:22][CH:23]=1)=[O:14].[CH:24]1([NH2:29])[CH2:28][CH2:27][CH2:26][CH2:25]1>>[CH:24]1([NH:29][CH2:2][CH2:3][CH2:4][O:5][C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[NH:12][C:13]([C:15]2[C:16]3[CH:17]=[CH:18][NH:19][C:20]=3[CH:21]=[CH:22][CH:23]=2)=[O:14])[CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 2906CyclopentylamineHCID 20098374HCID 20098374, compound

Product 1

HCID 20098394HCID 20098394, compound

Procedure

Using the procedure of Example 41, Step B, 4 g of the product of Step A of Example 41 and 2.11 ml of cyclopentylamine were reacted to obtain 3.3 g of N-[2-[3-(cyclopentylamino)propoxy]phenyl]-1H-indol-4-carboxamide and then 2.8 g of its hydrochloride melting at 244° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-2a49bcfa3d4c4a12af638c137b52ce47
Source dataset
uspto-grants-1990_03
Patent number
US04908367

Reaction notes

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