反应详情

Under inert atmosphere, 1 g of 1-methyl-quinolin-2-one and 25 ml of benzene were mixed together and then 1.27 g of 2,4-bis-(4-methoxyphenyl)-2,4-dithioxo-1,3,2,4-dithiadiphos phetane (Laweseeon's reagent) were added all at once. After stirring at reflux for 1 hour, cooling, eliminating the solvent by distilling under reduced pressure and drying under a good vacuum and chromatographing, the residue was chromatographed on silica and eluted with a mixture of methylene chloride and ethyl acetate (1/1) to obtain 1 g of the product sought melting at 114° C.

1. temperatureat reflux for 1 hour
2. temperaturecooling
3. distillationby distilling under reduced pressure
4. customdrying under a good vacuum and chromatographing
5. customthe residue was chromatographed on silica
6. washeluted with a mixture of methylene chloride and ethyl acetate (1/1)