Acetone → HCID 19862979, compound

Participants

Reaction Steps

58 g (1 mole) of acetone and 36 g (0.2 mole) of p-tert.-butoxy-benzaldehyde are introduced into a 300 ml stirred autoclave, 5 g of zinc oxide and 1 g of 1% strength palladium on active charcoal are added and the mixture is heated to 160° C., with vigorous stirring, under 20 bar hydrogen pressure. After a reaction time of 2 hours, the reaction mixture is cooled, freed from catalyst by filtration, and subjected to fractional distillation. 19 g of 1-(4-tert.-butoxy-phenyl)-butan-3-one (yield: 43%) are obtained.

Provenance & Evidence