HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-Acetylaminonaphthalene-2-sulfonic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 6-Amino-2-naphthalenesulfonic acid | HCID 7116 | — |
| Reactant | 2-Naphthol | HCID 8663 | — |
| Reactant | 1-Naphthalenesulfonic acid, 2-hydroxy- | HCID 11278 | — |
| Reactant | Ammonium Bisulfite | HCID 10441651 | — |
| Product | 5-Acetylaminonaphthalene-2-sulfonic acid | HCID 235551 | — |
Reaction Steps
In a single-vessel process for preparing 2-acetaminophthalene-6-sulfonic acid of high purity by sulfonating 2-hydroxynaphthalene with concentrated sulfuric acid, converting the 2-hydroxynaphthalenesulfonic acid formed thereby with ammonia in the presence of ammonium hydrogensulfite into 2-aminonaphthalene-6-sulfonic acid (Bucherer reaction and N-acetylating the said 2-aminonaphthalene-6-sulfonic acid to give 2 acetaminonaphthalene-6-sulfonic acid, the improvement which comprises:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04908478 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-416bc47a863843e3870dabc05524ace4 |
| Source note | uspto-grants-1990_03 |