HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethylpiperazine → HCID 19776614, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethylpiperazine | HCID 79196 | — |
| Reactant | 7-Chloro-8-cyano-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid | HCID 15347191 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 19776614 | HCID 19776614 | — |
Reaction Steps
0.5 g of the product from Example 1 and 0.55 g of N-ethylpiperazine are boiled in 8 ml of dioxane for 3 hours. The mixture is then concentrated in vacuo. The residue is taken up in water and rendered neutral. The mixture is extracted with methylene chloride and the organic phase is separated off, dried over sodium sulphate and concentrated. 0.5 g of the title compound of melting point >300° C. remains.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04908366 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-58ab62c6d37b45ca8ed906434ad048d1 |
| Source note | uspto-grants-1990_03 |