HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzyl alcohol → 3(2H)-Pyridazinone, 4-chloro-2-(4-chloro-2-fluorophenyl)-5-((4-chlorophenyl)methoxy)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzyl alcohol | HCID 13397 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | HCID 22235203 | HCID 22235203 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3(2H)-Pyridazinone, 4-chloro-2-(4-chloro-2-fluorophenyl)-5-((4-chlorophenyl)methoxy)- | HCID 3065233 | 68.4% |
Reaction Steps
In 30 m, of N,N-dimethylformamide were dissolved 1.0 g (3.4 m mol) of 2-(4-chloro-2-fluorophenyl)-4,5-dichloro-3(2H)-pyridazinone and 0.48 g (3.4 m mol) of p-chlorobenzyl alcohol, and thereto was added 0.22 g of powdery potassium hydroxide. Then, the procedures in Synthesis Example 2 were repeated to give 920 mg of the intended compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04910201 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-b0180b1d1fc744d5acbe9169a7fd05f3 |
| Source note | uspto-grants-1990_03 |