HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 4-chloro-2-(4-chlorophenyl)-5-{(5-methyl-2-thienyl)-methoxyloxy}-3(2H)-pyridazinone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | (5-Methylthiophen-2-yl)methanol | HCID 528074 | — |
| Reactant | 4,5-Dichloro-2-(4-chlorophenyl)-3(2H)-pyridazinone | HCID 779402 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-chloro-2-(4-chlorophenyl)-5-{(5-methyl-2-thienyl)-methoxyloxy}-3(2H)-pyridazinone | HCID 19861813 | 73.2% |
Reaction Steps
The procedures in Synthesis Example 11 were repeated by using 2.0 g (7.3 m mol) of 2-(4-chlorophenyl)-4,5-dichloro-3(2H)-pyridazinone, 1.0 g (7.8 m mol) of 5-methyl-2-thiophene methanol, 0.4 g of potassium hydroxide and 80 ml of N,N-dimethylformamide to give 2.0 g of the intended product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04910201 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-2b5c07f79fd645308b09c3a742a547d2 |
| Source note | uspto-grants-1990_03 |