HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → 3(2H)-Pyridazinone, 2-(4-chlorophenyl)-5-((6-chloro-3-pyridinyl)methoxy)-4-iodo-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | (6-Chloropyridin-3-yl)methanol | HCID 177161 | — |
| Reactant | HCID 19861814 | HCID 19861814 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3(2H)-Pyridazinone, 2-(4-chlorophenyl)-5-((6-chloro-3-pyridinyl)methoxy)-4-iodo- | HCID 3078729 | 61.5% |
Reaction Steps
The procedures in Synthesis Example 2 were repeated by using 3.3 g (7.2 m mol) of 2-(4-chlorophenyl)-4,5-diiodo-3(2H)-pyridazinone, 1.1 g (7.7 m mol) of 6-chloro-3-pyridine-methanol, 0.4 g of potassium hydroxide and 80 ml of N,N-dimethylformamide to give 2.1 g of the intended product. (recrystallized from benzene)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04910201 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-f5e0699cc322480cb39f559056b61ebb |
| Source note | uspto-grants-1990_03 |