p-Chlorothiophenol → HCID 10942819, compound

Temperature

100 °C

Sodium p-chlorothiophenoxide was prepared from p-chlorothiophenol (4.3 g) in methanol (10 ml) and sodium methoxide (5.4 g of a 30% sodium methoxide solution) by evaporation in a rotary evaporator. The resulting salt was dissolved, together with 3,4-dimethoxy-4'-fluorobenzophenone (7.8 g) in dimethylformamide (30 ml), and the solution was heated at 100° C. for 3 hours. Then, the reaction mixture was poured into water, and the crystals which precipitated were recrystallized from ethanol.

1. customby evaporation
2. customin a rotary evaporator
3. dissolutionThe resulting salt was dissolved, together with 3,4-dimethoxy-4'-fluorobenzophenone (7.8 g) in dimethylformamide (30 ml)
4. additionThen, the reaction mixture was poured into water
5. customthe crystals which precipitated
6. customwere recrystallized from ethanol

ORD record

ord-31208f6518ec414e801a72b40185193b

Source dataset

uspto-grants-1990_03

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04910200