Acetic Anhydride → HCID 14424745, compound

HRID 1165483Notes

Reaction equation

HRID 1165483 reaction equation
[OH:1][C:2]1[C:7]2[N:8]=[C:9]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=3)[S:10][C:6]=2[CH:5]=[CH:4][CH:3]=1.[C:19](OC(=O)C)(=[O:21])[CH3:20]>>[C:19]([O:1][C:2]1[C:7]2[N:8]=[C:9]([C:11]3[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=3)[S:10][C:6]=2[CH:5]=[CH:4][CH:3]=1)(=[O:21])[CH3:20]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 14424740HCID 14424740, compound

Product 1

HCID 14424745HCID 14424745, compound

Procedure

The 4-hydroxy-2-(4-methoxyphenyl)benzothiazole (4.0 g) obtained in Example 2 was added to 40 ml of acetic anhydride, and the mixture was refluxed for 1 hour. After the reaction, the reaction mixture was dried under reduced pressure. The residue was washed with a small amount of cyclohexane, and recrystallized from cyclohexane and ethyl acetate to give 4.0 g of 4-acetoxy-2-(4-methoxyphenyl)benzothiazole.

Workup

  1. temperaturethe mixture was refluxed for 1 hour
  2. customAfter the reaction
  3. customthe reaction mixture was dried under reduced pressure
  4. washThe residue was washed with a small amount of cyclohexane
  5. customrecrystallized from cyclohexane and ethyl acetate

Sources & evidence

ORD record
ord-691d56a37d7d4b45bd358d0f0fbc282b
Source dataset
uspto-grants-1990_03
Patent number
US04910211

Reaction notes

Loading…