Acetic Anhydride → HCID 14424747, compound

HRID 1165485Notes

Reaction equation

HRID 1165485 reaction equation
[OH:1][C:2]1[C:7]2[N:8]=[C:9]([C:11]3[CH:20]=[CH:19][C:14]([C:15]([O:17][CH3:18])=[O:16])=[CH:13][CH:12]=3)[S:10][C:6]=2[CH:5]=[CH:4][CH:3]=1.[C:21](OC(=O)C)(=[O:23])[CH3:22]>>[C:21]([O:1][C:2]1[C:7]2[N:8]=[C:9]([C:11]3[CH:20]=[CH:19][C:14]([C:15]([O:17][CH3:18])=[O:16])=[CH:13][CH:12]=3)[S:10][C:6]=2[CH:5]=[CH:4][CH:3]=1)(=[O:23])[CH3:22]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 14424744HCID 14424744, compound

Product 1

HCID 14424747HCID 14424747, compound

Procedure

The methyl 4-(4-hydroxybenzothiazol-2-yl)benzoate (2.5 g) obtained in Example 4 was added to 30 ml of acetic anhydride, and the mixture was refluxed for 2 hours. After the reaction, the reaction mixture was dried under reduced pressure. The residue was washed with a small amount of cyclohexane, and recrystallized from cyclohexane and ethyl acetate to give 2.3 g of methyl 4-(4-acetoxybenzothiazol-2-yl)benzoate.

Workup

  1. temperaturethe mixture was refluxed for 2 hours
  2. customAfter the reaction
  3. customthe reaction mixture was dried under reduced pressure
  4. washThe residue was washed with a small amount of cyclohexane
  5. customrecrystallized from cyclohexane and ethyl acetate

Sources & evidence

ORD record
ord-fb753191c4924234856c754cf469ea76
Source dataset
uspto-grants-1990_03
Patent number
US04910211

Reaction notes

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