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HRID1165505

反应详情

EQUATION

反应方程式

HRID 1165505 的结构方程式

REACTANTS

反应物

1
结构：C[C@]12CC[C@H]3[C@@H](CCC4=CC(O)CC[C@@]43C)[C@@H]1CC[C@@H]2CO
HCID14801334

未命名化合物

PRODUCTS

生成物

1
结构：C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@@]43C)[C@@H]1CC[C@@H]2CO
HCID14377617

未命名化合物

收率 96.6%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[Mn+4].[O-2].[O-2]
催化剂HCID178418406

未命名化合物

结构：ClC(Cl)Cl
溶剂HCID6212

Chloroform

CHCl3

PROCEDURE

实验过程

A solution of 17β-(hydroxymethyl)androst-4-ene-3-ol (27 g, 0.089 mol) in 1200 ml trichloromethane was treated with activated manganese dioxide (66 g). After 3 hours the mixture was filtered. Concentration afforded 26 g (96%) of 3-oxo-17β-(hydroxymethyl)-4-androstene (m.p. 151° C.).

WORKUP

后处理

  1. filtrationAfter 3 hours the mixture was filtered
  2. concentrationConcentration