HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxystyrene → HCID 19861948, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxystyrene | HCID 12507 | — |
| Reactant | 3-methoxybicyclo[4.2.0]octa-1,3,5-triene-7-carbonitrile | HCID 2753015 | — |
| Product | HCID 19861948 | HCID 19861948 | — |
Reaction Steps
A mixture of 4-methoxybenzocyclobutane-1-carbonitrile (16 g) and 4-methoxystyrene (23.5 g) was stirred and heated at 175° for 45 minutes. The mixture was cooled, and purified by flash column chromatography on silica (K60), eluting with a mixture of ethyl acetate and petroleum ether (b.p. 40°-60°), 1:9 by volume, to give 1,2,3,4-tetrahydro-6-methoxy-2-(4-methoxyphenyl)naphthalene-1-carbonitrile, m.p. 127°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04910212 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-51d1c30401d049fd8d6d42bebedf0542 |
| Source note | uspto-grants-1990_03 |