2,3-Quinolinedicarboxylic acidtrihydrate → Furo[3,4-b]quinoline-1,3-dione

Participants

Reaction Conditions

Reaction Steps

A mixture of 2,3-quinolinedicarboxylic acid-trihydrate (0.141 mol) in acetic anhydride (125 mL) is heated at 85° C. for one-half hour and then at 100° C. for one hour. The reaction mixture is then cooled to room temperature, filtered and the solids washed with ethyl ether to afford the desired 2,3-quinolinedicarboxylic anhydride, mp 225°-228° C.

Provenance & Evidence