1-Cyclopropyl-2-methoxyethan-1-amine → 2-chloro-N-(1-cyclopropyl-2-methoxyethyl)-7-(4-fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine

HRID 116561Notes

Reaction equation

HRID 116561 reaction equation
[CH:19]1([CH:22]([CH2:23][O:24][CH3:25])[NH2:26])[CH2:20][CH2:21]1.[Cl:1][c:2]1[n:3][c:4]([Cl:18])[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1)[CH2:9][CH2:10]2>>[Cl:1][c:2]1[n:3][c:4]([NH:26][CH:22]([CH:19]2[CH2:20][CH2:21]2)[CH2:23][O:24][CH3:25])[c:5]2[c:6]([n:7]1)[CH:8]([c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1)[CH2:9][CH2:10]2

Participants

3

Reactant 2

HCID 534149871-Cyclopropyl-2-methoxyethan-1-amineHCID 580754242,4-Dichloro-7-(4-fluorophenyl)-6,7-dihydro-5H-cyclopenta[D]pyrimidine

Product 1

HCID 580756552-chloro-N-(1-cyclopropyl-2-methoxyethyl)-7-(4-fluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-amine

Sources & evidence

ORD record
ord-83e135c535a54005add36dc9a5bc993e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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