Sodium Hydroxide → HCID 19994209, compound

HRID 1165613Notes

Reaction equation

HRID 1165613 reaction equation
[NH2:1][CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[CH:9][C:8]([N:11]2[C:15](=O)[CH2:14][O:13][CH-]2)=[CH:7][C:6]=1[N+:17]([O-:19])=[O:18].[OH-].[Na+]>C(O)C>[NH2:1][CH2:2][CH2:3][NH:4][C:5]1[CH:10]=[CH:9][C:8]([NH:11][CH2:15][CH2:14][OH:13])=[CH:7][C:6]=1[N+:17]([O-:19])=[O:18]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 178511330HCID 178511330, compound

Product 1

HCID 19994209HCID 19994209, compoundYield 9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Conditions

Temperature
95 °C

Procedure

0.4 mole (10.64 g) of N-[4-(β-aminoethyl)amino-3-nitrophenyl]oxazolidone, prepared according to Example 10, is added to 27 ml of 3N sodium hydroxide and 11 ml of 96° strength ethanol. After being heated for 45 minutes at 95° C., the solution is poured onto ice, and the precipitate obtained is drained and then washed with iced water. After being dried under vacuum, 0.036 mole (8.7 g) of the expected product is obtained. It melts at 112° C.

Workup

  1. additionthe solution is poured onto ice
  2. customthe precipitate obtained
  3. washwashed with iced water
  4. customAfter being dried under vacuum

Sources & evidence

ORD record
ord-d2166fecdce948edb1aa1bcc3ce8e8d9
Source dataset
uspto-grants-1990_03
Patent number
US04910341

Reaction notes

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