HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfate → ethyl 3-methyl-3H-naphth[1,2-g]indol-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfate | HCID 6497 | — |
| Reactant | ethyl 3H-naphth[1,2-g]indole-2-carboxylate | HCID 20065898 | — |
| Solvent | Methylenechloride Hexane | HCID 21226440 | — |
| Product | ethyl 3-methyl-3H-naphth[1,2-g]indol-2-carboxylate | HCID 20065897 | 74.5% |
Reaction Steps
Using the procedure outlined in Example 34A except that dimethyl sulfate was used as the alkylating agent, ethyl 3H-naphth[1,2-g]indole-2-carboxylate (H. G. Pars Pharmaceutical Laboratories, Inc.) gave a 74.5% yield of ethyl 3-methyl-3H-naphth[1,2-g]indol-2-carboxylate, mp 136°-138°, (CH2Cl2 /hexane), (C,H,N).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04910218 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-44b4821c008a486cbd4ead9ff45eb067 |
| Source note | uspto-grants-1990_03 |