Dimethyl Sulfate → HCID 15170274, compound

HRID 1165666Notes

Reaction equation

HRID 1165666 reaction equation
S(OC)(O[CH3:5])(=O)=O.[NH:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]3[S:19][C:18]4[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=4[C:15]3=2)[CH:10]=[C:9]1[C:24]([O:26][CH2:27][CH3:28])=[O:25]>C1(C)C=CC=CC=1>[CH3:5][N:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]3[S:19][C:18]4[CH:20]=[CH:21][CH:22]=[CH:23][C:17]=4[C:15]3=2)[CH:10]=[C:9]1[C:24]([O:26][CH2:27][CH3:28])=[O:25]

Participants

4

Reactant 2

HCID 6497Dimethyl SulfateHCID 13412147HCID 13412147, compound

Product 1

HCID 15170274HCID 15170274, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Using the procedure outlined in Example 34A except that dimethyl sulfate was used as the alkylating agent, ethyl 1H-[1]benzothieno[2,3-g]indole-2-carboxylate (H. G. Pars Pharmaceutical Laboratories, Inc.) gave a quantitative yield of ethyl 1-methyl-1H-[1]benzothieno[2,3-g]indole-2-carboxylate, mp 85°-86°, (PhCH3), (C,H,N).

Sources & evidence

ORD record
ord-186e7994810d4bac84a6f3ed67b4a074
Source dataset
uspto-grants-1990_03
Patent number
US04910218

Reaction notes

Loading…