Dicyclohexylcarbodiimide → HCID 14346840, 화합물

HRID 1165710노트

반응식

HRID 1165710 반응식
C1(N=C=NC2CCCCC2)CCCCC1.[F:16][CH:17]([F:38])[O:18][C:19]1[CH:20]=[N:21][C:22]([C:28]2[NH:29][C:30](=[O:37])[C:31]([CH:34]([CH3:36])[CH3:35])([CH3:33])[N:32]=2)=[C:23]([CH:27]=1)[C:24](O)=[O:25]>C(Cl)Cl>[F:16][CH:17]([F:38])[O:18][C:19]1[CH:27]=[C:23]2[C:24](=[O:25])[N:29]3[C:30](=[O:37])[C:31]([CH:34]([CH3:36])[CH3:35])([CH3:33])[N:32]=[C:28]3[C:22]2=[N:21][CH:20]=1

참가 물질

4

반응물 2

HCID 10868DicyclohexylcarbodiimideHCID 13852376HCID 13852376, 화합물

생성물 1

HCID 14346840HCID 14346840, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

Dicyclohexylcarbodiimide (1.07 g, 5 mmol) in 20 mL CH2Cl2 is added to a stirred solution containing 1.54 g (4.7 mmol) 5-(difluoromethoxy)-2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)nicotinic acid in 30 mL CH2Cl2 under nitrogen at room temperature. The mixture is stirred overnight, filtered and concentrated to give the product, 7-(difluoromethoxy)-2-isopropyl-2-methyl-5H-imidazo[1',2':1,2]pyrrolo[3,4-b]pyridine-3(2H), 5-dione.

후처리

  1. filtrationfiltered
  2. concentrationconcentrated

출처 및 근거

ORD 기록
ord-7ff51dad34be40a28b272aa2d9e79d27
출처 데이터셋
uspto-grants-1990_03
특허 번호
US04911753

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