HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 3,3'-Difluoro-4,4'-dihydroxybiphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 3,3'-Difluoro-4,4'-dimethoxy-1,1'-biphenyl | HCID 19752045 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3,3'-Difluoro-4,4'-dihydroxybiphenyl | HCID 520956 | — |
Reaction Steps
10.0 g of 3,3'-difluoro-4,4'-dimethoxybiphenyl was dissolved in 150 ml of dioxane, and 150 ml of 48% hydrobromic acid was added. The mixture was heated under reflux for 50 hours. After the reaction, the reaction mixture was subjected to evaporation under reduced pressure. The residue was fully washed with water to obtain the desired 3,3'-difluoro-4,4'-dihydroxybiphenyl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04911862 |
| Source dataset | uspto-grants-1990_03 |
| ORD ID | ord-6eca85ce9df04843ab55d647934c091b |
| Source note | uspto-grants-1990_03 |