Acetic Anhydride → HCID 70360371, compound

Participants

Reaction Steps

Analogously to Example 9, 2.2 g of 17-benzoyloxy-11β,21-dihydroxy-6α-methyl-4-pregnene-3,20-dione is reacted with acetic anhydride and worked up as usual. The crude product is purified on 350 g of silica gel with a methylene chloride-acetone gradient (0-8% acetone), thus isolating 1.6 g of 21-acetoxy-17-benzoyloxy-11β-hydroxy-6α-methyl-4-pregnene-3,20-dione, mp 210° C.

Provenance & Evidence