2-Bromothiazole → 1,1-Dimethylethyl 4-hydroxy-4-(2-thiazolyl)-1-piperidinecarboxylate

HRID 116575Notes

Reaction equation

HRID 116575 reaction equation
[Br:15][c:16]1[s:17][cH:18][cH:19][n:20]1.[O:1]=[C:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1>>[OH:1][C:2]1([c:16]2[s:17][cH:18][cH:19][n:20]2)[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 764302-BromothiazoleHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 574237961,1-Dimethylethyl 4-hydroxy-4-(2-thiazolyl)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-6d47467963554defadf6236396db1baa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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