HCID 178526409, compound → HCID 178507218, compound

Participants

Reaction Steps

A solution of 7,8,9,10-tetrahydro-2,3-dihydroxy-6-nitrobenzo(f)quinoxaline (1.5 g, 5.7 mmol) in 50 ml of N,N-dimethylformamide was hydrogenated at atmospheric pressure and room temperature in the presence of 5% palladium-on-charcoal. The catalyst was filtered off, and the filtrate was evaporated to dryness. The residue was triturated with water, the solid was collected and washed with water, and ethanol affording 1.2 g (90%) of the amino compound; m.p. > 300° C.; 1H-NMR (DMSO-d6): 1.7-2.0 (m,4H,2×CH2), 2.5-2.8 (m,4H, 2 × CH2), 4.97 (broad s, 2H, NH2), 6.53 (s, 1H, H-5), 10.5 (broad s, 1H, 0H), 11.4 (broad s, 1H, 0H).

Provenance & Evidence