Oxalic acid dihydrate → HCID 178514692, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 5,0 g (21,0 mmol) 1,2-diamino-naphthalene-5-sulphonamide hydrochloride salt and 6,0 g oxalic acid dihydrate in 200 ml 2N hydrochloric acid was refluxed for 2,5 h. After cooling to 25° C., the precipitate was filtered off and washed with water. The crude product was recrystallized (dimethylformamide-water) to give 7,5 g (69%) 2,3-dihydroxy-7-sulphamoyl-benzo[f]quinoxaline, m.p. 420° C. NMR (DMSO-d6): 12,3 (2H, broad s), 8,9 (1H,d), 8,5 (1H,d), 8,2 (1H,d), 7,7 (4H,m).

Provenance & Evidence