Hydrochloric Acid → HCID 178507220, compound

Participants

Reaction Steps

A solution of 0,5 g (1,49 mmol) 2,3-dihydroxy-6-nitro-7-sulphamoyl-benzo[f]quinoxaline in 5 ml dimethylformamide was hydrogenated at atm. pressure by using ca. 1 g Ra-Ni as a catalyst. The filtered reaction mixture was added 5 ml 1N hydrochloric acid, and then evaporated in vacuo. The crude product was recrystallized (dimethylformamide-water) to give 0,2 g (40%) 6-amino-2,3-dihydroxy-7-sulphamoyl-benzo[f]quinoxaline as a hydrochloride salt. MS: (m/e) 306 (M+ ; 75%). NMR (DMSO-6): 11,8 (2H, broad s), 8.7 (1H,d), 8.2 (1H,d), 7.6 (3H,m), 6.93 (1H,s), 6.1 (2H, broad s).

Provenance & Evidence