2-(2-Chloroethyl)-1-benzofuran → HCID 14154493, compound

HRID 1165871Notes

Reaction equation

HRID 1165871 reaction equation
[CH3:1][NH:2][CH2:3][CH2:4][CH2:5][N:6]1[CH2:15][CH2:14][C:13]2[C:8](=[CH:9][C:10]([O:18][CH3:19])=[C:11]([O:16][CH3:17])[CH:12]=2)[C:7]1=[O:20].[Cl:21][CH2:22][CH2:23][C:24]1[O:28][C:27]2[CH:29]=[CH:30][CH:31]=[CH:32][C:26]=2[CH:25]=1>>[ClH:21].[CH3:1][N:2]([CH2:22][CH2:23][C:24]1[O:28][C:27]2[CH:29]=[CH:30][CH:31]=[CH:32][C:26]=2[CH:25]=1)[CH2:3][CH2:4][CH2:5][N:6]1[CH2:15][CH2:14][C:13]2[C:8](=[CH:9][C:10]([O:18][CH3:19])=[C:11]([O:16][CH3:17])[CH:12]=2)[C:7]1=[O:20]

Participants

3

Reactant 2

HCID 1887222-(2-Chloroethyl)-1-benzofuranHCID 14154484HCID 14154484, compound

Product 1

HCID 14154493HCID 14154493, compound

Procedure

Prepared from 2-(N-methyl-3-amino-propyl)-6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydro-isoquinoline and 2-(2-chloro-ethyl)-benzo[b]furan analogously to Example 1.

Sources & evidence

ORD record
ord-517c34734d2b4a5cae06221fc57ad1a8
Source dataset
uspto-grants-1990_03
Patent number
US04912115

Reaction notes

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