Dichloromethane → methyl 5-[5-[[2-[3,5-bis(trifluoromethyl)phenyl]-2-methylpropanoyl]-methylamino]-4-(4-fluoro-2-methylphenyl)-2-pyridinyl]-3,4-dihydro-2H-pyrrole-2-carboxylate
Reaction equation
[Cl:52][CH2:53][Cl:54].[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[N:16]([c:17]2[c:18](-[c:39]3[c:40]([CH3:46])[cH:41][c:42]([F:45])[cH:43][cH:44]3)[cH:19][c:20]([C:23]#[C:24][CH2:25][CH:26]([C:27](=[O:28])[O:29][CH3:30])[NH:31][C:32]([O:33][C:34]([CH3:35])([CH3:36])[CH3:37])=[O:38])[n:21][cH:22]2)[CH3:47])([CH3:48])[CH3:49])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:50])[F:51]>>[F:1][C:2]([c:3]1[cH:4][c:5]([C:13]([C:14](=[O:15])[N:16]([c:17]2[c:18](-[c:39]3[c:40]([CH3:46])[cH:41][c:42]([F:45])[cH:43][cH:44]3)[cH:19][c:20]([C:23]3=[N:31][CH:26]([C:27](=[O:28])[O:29][CH3:30])[CH2:25][CH2:24]3)[n:21][cH:22]2)[CH3:47])([CH3:48])[CH3:49])[cH:6][c:7]([C:9]([F:10])([F:11])[F:12])[cH:8]1)([F:50])[F:51]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-47bddfcd55644a3f8f5e92843eef7ddd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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