HCID 178505924, compound → 2-(2-Aminoethylthio)-1-(phenylethyl)imidazole

HRID 1165931Notes

Reaction equation

HRID 1165931 reaction equation
FC1C=[C:4](C=C(F)C=1)[CH2:5][N:6]1C=CN=C1S.[C:16]1([CH2:22][CH2:23][N:24]2[CH:28]=[CH:27][N:26]=[C:25]2[SH:29])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[NH2:6][CH2:5][CH2:4][S:29][C:25]1[N:24]([CH2:23][CH2:22][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:28]=[CH:27][N:26]=1

Participants

3

Reactant 2

HCID 178505924HCID 178505924, compoundHCID 178527874HCID 178527874, compound

Product 1

HCID 540018752-(2-Aminoethylthio)-1-(phenylethyl)imidazole

Procedure

The Example 1 process wherein 1-(3,5-difluorobenzyl)-2-mercaptoimidazole is replaced by 1-(phenylethyl)-2-mercaptoimidazole yields 2-(2-aminoethylthio)-1-(phenylethyl)imidazole.

Sources & evidence

ORD record
ord-df0ce82b3bfb481db287636022b01d2e
Source dataset
uspto-grants-1990_03
Patent number
US04912226

Reaction notes

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