HCID 178491962, compound → 2-(2-Aminoethylthio)-1-(4-methoxyphenyl)imidazole

HRID 1165934Notes

Reaction equation

HRID 1165934 reaction equation
FC1C=[C:4](C=C(F)C=1)[CH2:5][N:6]1C=CN=C1S.[CH3:16][O:17][C:18]1[CH:23]=[CH:22][C:21]([N:24]2[CH:28]=[CH:27][N:26]=[C:25]2[SH:29])=[CH:20][CH:19]=1>>[NH2:6][CH2:5][CH2:4][S:29][C:25]1[N:24]([C:21]2[CH:22]=[CH:23][C:18]([O:17][CH3:16])=[CH:19][CH:20]=2)[CH:28]=[CH:27][N:26]=1

Participants

3

Reactant 2

HCID 178491962HCID 178491962, compoundHCID 178505924HCID 178505924, compound

Product 1

HCID 198613892-(2-Aminoethylthio)-1-(4-methoxyphenyl)imidazole

Procedure

The Example 1 procedure wherein 1-(3,5-difluorobenzyl)-2-mercaptoimidazole is replaced by 1-(4-methoxyphenyl)-2-mercaptoimidazole yields 2-(2-aminoethylthio)-1-(4-methoxyphenyl)imidazole.

Sources & evidence

ORD record
ord-753c6feee6224d7dba205b92e1f6494c
Source dataset
uspto-grants-1990_03
Patent number
US04912226

Reaction notes

Loading…