Aniline → HCID 69681043, compound

HRID 1166010Notes

Reaction equation

HRID 1166010 reaction equation
N1[C:10]2[C:5](=[CH:6]C=CC=2)[CH2:4][CH2:3][CH2:2]1.[NH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>CC(C)=O>[CH3:6][C:5]1([CH3:10])[CH2:4][CH:3]([CH3:2])[CH:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH2:16]2)[NH:11]1

Participants

4

Reactant 2

HCID 6115AnilineHCID 694601,2,3,4-Tetrahydroquinoline

Product 1

HCID 69681043HCID 69681043, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

The tetrahydroquinoline skeleton can be dehydration-condensed with aniline and acetone and then the obtained product is reduced to obtain corresponding 2,2,4-trimethyltetrahydroquinoline according to a method described in Organic Synthesis Collective Volume, Vol. III, p. 328.

Sources & evidence

ORD record
ord-59edcb24ebd14d1d914fcfad7f276c76
Source dataset
uspto-grants-2003_09
Patent number
US06613313B2

Reaction notes

Loading…