4-(1H-Pyrazol-1-yl)benzaldehyde → 3-(4-Isoquinolinyl)acrolein

HRID 1166125Notes

Reaction equation

HRID 1166125 reaction equation
[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]=O)=[CH:3][N:2]=1.N1(C2C=C[C:21]([CH:22]=[O:23])=CC=2)C=CC=N1>>[CH:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]=[CH:21][CH:22]=[O:23])=[CH:3][N:2]=1

Participants

3

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 10868870Isoquinoline-4-carbaldehyde

Product 1

HCID 545366983-(4-Isoquinolinyl)acrolein

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-isoquinolinecarboxaldehyde for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 184 (M+H)+.

Sources & evidence

ORD record
ord-5751a9430c134cb1825bc8a2c700a9d8
Source dataset
uspto-grants-2003_09
Patent number
US06613747B2

Reaction notes

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