4-(1H-Pyrazol-1-yl)benzaldehyde → 3-[4-(4-Methoxy-2-pyrimidinyl)phenyl]-2-propenal

HRID 1166131Notes

Reaction equation

HRID 1166131 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][N:6]=[C:5]([C:9]2[CH:16]=[CH:15][C:12]([CH:13]=O)=[CH:11][CH:10]=2)[N:4]=1.N1(C2C=C[C:25]([CH:26]=[O:27])=CC=2)C=CC=N1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][N:6]=[C:5]([C:9]2[CH:16]=[CH:15][C:12]([CH:13]=[CH:25][CH:26]=[O:27])=[CH:11][CH:10]=2)[N:4]=1

Participants

3

Reactant 2

HCID 27764774-(1H-Pyrazol-1-yl)benzaldehydeHCID 226310554-(4-Methoxypyrimidin-2-YL)benzaldehyde

Product 1

HCID 739903573-[4-(4-Methoxy-2-pyrimidinyl)phenyl]-2-propenal

Procedure

The title compound was prepared by a procedure analogous to Reference Example 30 by substituting 4-(4-methoxy-2-pyrimidinyl)benzaldehyde (prepared as described in Reference Example 13) for the 4-(1H-pyrazol-1-yl)-benzaldehyde of Reference Example 30. MS 241 (M+H)+.

Sources & evidence

ORD record
ord-954e62b591cc46489c5c7d937af256c7
Source dataset
uspto-grants-2003_09
Patent number
US06613747B2

Reaction notes

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