Acetaldehyde → HCID 21024366, compound

HRID 1166667Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:27])[C:5]1[CH:10]=[CH:9][C:8]([NH:11][C:12]2[CH:21]=[CH:20][C:19]3[C:18]([CH:22]([CH3:24])[CH3:23])=[CH:17][CH2:16][C:15]([CH3:26])([CH3:25])[C:14]=3[CH:13]=2)=[CH:7][CH:6]=1)[CH3:2].[CH:28](=O)[CH3:29]>>[CH2:1]([O:3][C:4](=[O:27])[C:5]1[CH:6]=[CH:7][C:8]([N:11]([CH2:28][CH3:29])[C:12]2[CH:21]=[CH:20][C:19]3[C:18]([CH:22]([CH3:23])[CH3:24])=[CH:17][CH2:16][C:15]([CH3:25])([CH3:26])[C:14]=3[CH:13]=2)=[CH:9][CH:10]=1)[CH3:2]

Participants

Reactant 2

HCID 177Acetaldehyde

HCID 21024368HCID 21024368, compound2×

Product 1

HCID 21024366HCID 21024366, compound

Procedure

Following General Procedure M, 4-(5-isopropyl-8,8-dimethyl-7,8-dihydro-naphthalen-2-ylamino)-benzoic acid ethyl ester (Compound 79, 10 mg, 0.06 mmol), was reacted with acetaldehyde to give the title compound as a yellow oil.

Sources & evidence

ORD record: ord-bae03833da5e461a921187a90bb21ab2
Source dataset: uspto-grants-2003_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06613917B1

Reaction notes

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